Anticuerpos irregulares en pacientes transfundidos: un enfoque desde la prevalencia, características clínicas y diagnóstico de los receptors

  • Tanyi Mercedes Navarrete Bermúdez
  • Jazmín Castro Jalca

Abstract

Los anticuerpos irregulares pueden dificultar la búsqueda de sangre compatible ocasionando una mayor carga de trabajo para el área de Medicina transfusional y un incremento de los costos. La alta demanda de transfusión de sangre conlleva a un alto riesgo de aloinmunización en la población, provocada por una gran variedad de antígenos de baja frecuencia que pueden provocar reacciones hemolíticas transfusional es incluso, causar la muerte del receptor. Este estudio tuvo por objetivo describir los anticuerpos irregulares en pacientes transfundidos de acuerdo a su prevalencia, características clínicas y el diagnóstico de los receptores. Se utilizó un diseño de narrativa documental, a través del cual se buscó identificar la prevalencia, características clínicas y diagnóstico de anticuerpos irregulares en pacientes transfundidos a nivel nacional e internacional.

Las bases de datos y motores de búsqueda consultados fueron Medline (PubMed), Science Directy Scielo, en donde se analizó los artículos a través de palabras clave. A partir del análisis se ha logrado comprender que los anticuerpos irregulares más comunes son:Rh(Anti-E,Anti-C,Anti-D,Anti-c,Anti-eyAnti-Cw);Lutheran(Anti-Lua); Kell (Anti-K, Anti-K1 y Anti-Kpa); Duffy (Anti Fy, Anti-Fy1, Anti-Fya y Anti-Fyb); MNS(Anti-MyAnti-S);Lewis(Anti-Le,Anti-LeayAnti-Leb);yKidd(Anti-Jka. Finalmente, también se logró asumir que, los métodos de detección de anticuerpos irregulares que más se utilizan técnicas de aglutinación en tubo, en columna o en micro- placa, con etapas a temperatura ambiente, 37°C y antiglobulina humana y en algunos servicios la técnica de aglutinación en columna de gel.

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Author Biographies

Tanyi Mercedes Navarrete Bermúdez

Universidad Estatal del Sur de Manabí, Instituto de Posgrado, Facultad de Ciencias de la Salud, Maestría en Ciencias del Laboratorio Clínico, Jipijapa, Manabí.

Jazmín Castro Jalca

Magíster en Epidemiologia, Licenciada en Laboratorio Clínico, Carrera de Laboratorio Clínico, Facultad de Ciencias de la Salud, Universidad Estatal del Sur de Manabí, Jipijapa, Ecuador.

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Published
2022-11-20
How to Cite
Tanyi Mercedes Navarrete Bermúdez, & Jazmín Castro Jalca. (2022). Anticuerpos irregulares en pacientes transfundidos: un enfoque desde la prevalencia, características clínicas y diagnóstico de los receptors. Revista Cien´tifica FIPCAEC (Fomento De La investigación Y publicación En Ciencias Administrativas, Económicas Y Contables), 7(4), 877-907. Retrieved from https://fipcaec.com/index.php/fipcaec/article/view/666
Section
Artículos de Investigación