Concentraciones de dímero d y tiempo de protrombina en pacientes hospitalizados por covid-19
Palabras clave:
Dímero D; Diabetes; COVID-19; Pronóstico; Letalidad.
Resumen
La crisis sanitaria por la COVID-19, debido a su rápida expansión y al poco conocimiento de esta nueva enfermedad, ocasionó la muerte de gran cantidad de personas alrededor del mundo, motivo por el cual se ha generado la necesidad de identificar posibles biomarcadores que permitan dar un pronóstico de la gravedad de esta infección. El objetivo del presente estudio fue analizar las concentraciones de dímero D y el tiempo de protrombina como pronóstico de letalidad en pacientes hospitalizados con COVID-19. El estudio consistió en una investigación de diseño documental con carácter descriptivo y exploratorio el cual permitió seleccionar artículos publicados año 2018-2022, seleccionados bajo criterios de inclusión y exclusión de bases de datos científicas. Se evidencia una correlación en la alteración de los valores de dímero D, con la tasa de letalidad del 65,77% que se encontró en promedio en los diferentes estudios. La fisiopatología de la COVID-19 incluye en algunos individuos el desarrollo de una sobre regulación del proceso inflamatorio con la consecuente tormenta de citoquinas que favorece la activación de la cascada de coagulación, las alteraciones en las concentraciones del dímero D se encuentran relacionados con casos graves y en especial ante la presencia de comorbilidades subyacentes.
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24. Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., & Manson, J. J. (2020). COVID-19: Consider cytokine storm syndromes and immunosuppression. The Lancet, 395(10229), 1033-1034. https://doi.org/10.1016/S0140-6736(20)30628-0
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Publicado
2022-11-20
Cómo citar
Angélica Yesenia Rodas Toapanta, & Yoiler Batista Garcet. (2022). Concentraciones de dímero d y tiempo de protrombina en pacientes hospitalizados por covid-19. Revista Científica FIPCAEC (Fomento De La investigación Y publicación científico-técnica multidisciplinaria). ISSN : 2588-090X . Polo De Capacitación, Investigación Y Publicación (POCAIP), 7(4), 1155-1177. Recuperado a partir de https://fipcaec.com/index.php/fipcaec/article/view/678
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Artículos de Investigación
